Jennifer Doudna, UC Berkeley (Nobel Prize in Chemistry, 2020)
There are 104 publications in this collection, published between 2009 and 2022. Showing 1 - 50.
Cofsky, Joshua C; Soczek, Katarzyna M; Knott, Gavin J; Nogales, Eva; Doudna, Jennifer A: CRISPR–Cas9 bends and twists DNA to read its sequence, 2022
Rubin, Benjamin E; Diamond, Spencer; Cress, Brady F; Crits-Christoph, Alexander; Lou, Yue Clare; Borges, Adair L et al.: Species- and site-specific genome editing in complex bacterial communities, 2022
Servellita, Venice; Syed, Abdullah M; Morris, Mary Kate; Brazer, Noah; Saldhi, Prachi; Garcia-Knight, Miguel et al.: Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants, 2022
Amen, Alexandra M; Fellmann, Christof; Soczek, Katarzyna M; Ren, Shawn M; Lew, Rachel J; Knott, Gavin J et al.: Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage, 2021
Hamilton, Jennifer R; Tsuchida, Connor A; Nguyen, David N; Shy, Brian R; McGarrigle, E Riley; Sandoval Espinoza, Cindy R et al.: Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering, 2021
Liu, Tina Y; Knott, Gavin J; Smock, Dylan CJ; Desmarais, John J; Son, Sungmin; Bhuiya, Abdul et al.: Accelerated RNA detection using tandem CRISPR nucleases., 2021
Liu, Tina Y; Knott, Gavin J; Smock, Dylan CJ; Desmarais, John J; Son, Sungmin; Bhuiya, Abdul et al.: Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases, 2021
Wang, Joy Y; Hoel, Christopher M; Al-Shayeb, Basem; Banfield, Jillian F; Brohawn, Stephen G; Doudna, Jennifer A: Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex, 2021
Al-Shayeb, Basem; Sachdeva, Rohan; Chen, Lin-Xing; Ward, Fred; Munk, Patrick; Devoto, Audra et al.: Clades of huge phages from across Earth’s ecosystems, 2020
Doudna, Jennifer A: The promise and challenge of therapeutic genome editing, 2020
Hamilton, Jennifer R; Doudna, Jennifer A: Knocking out barriers to engineered cell activity, 2020
Ivanov, Ivan E; Wright, Addison V; Cofsky, Joshua C; Aris, Kevin D Palacio; Doudna, Jennifer A; Bryant, Zev: Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling, 2020
Watters, Kyle E; Shivram, Haridha; Fellmann, Christof; Lew, Rachel J; McMahon, Blake; Doudna, Jennifer A: Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes, 2020
Amen, Alexandra; Lew, Rachel; Ren, Shawn; McKinney, Andrew; Mancini, Andrew; Doudna, Jennifer et al.: GENE-43. TARGETING GABPb1L INHIBITS IN VIVO GROWTH OF TERT PROMOTER MUTANT GLIOBLASTOMA, 2019
Cao, Yuhong; Ma, Enbo; Cestellos-Blanco, Stefano; Zhang, Bei; Qiu, Ruoyi; Su, Yude et al.: Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules, 2019
Cao, Yuhong; Ma, Enbo; Cestellos-Blanco, Stefano; Qiu, Ruoyi; Su, Yude; Doudna, Jennifer A et al.: Reply to Nathamgari et al.: Nanopore electroporation for intracellular delivery of biological macromolecules, 2019
Chen, Lin-Xing; Al-Shayeb, Basem; Méheust, Raphaël; Li, Wen-Jun; Doudna, Jennifer A; Banfield, Jillian F: Candidate Phyla Radiation Roizmanbacteria From Hot Springs Have Novel and Unexpectedly Abundant CRISPR-Cas Systems, 2019
Heler, Robert; Wright, Addison V; Vucelja, Marija; Doudna, Jennifer A; Marraffini, Luciano A: Spacer Acquisition Rates Determine the Immunological Diversity of the Type II CRISPR-Cas Immune Response, 2019
Jiang, Fuguo; Liu, Jun-Jie; Osuna, Beatriz A; Xu, Michael; Berry, Joel D; Rauch, Benjamin J et al.: Temperature-Responsive Competitive Inhibition of CRISPR-Cas9, 2019
Knott, Gavin J; Thornton, Brittney W; Lobba, Marco J; Liu, Jun-Jie; Al-Shayeb, Basem; Watters, Kyle E et al.: Broad-spectrum enzymatic inhibition of CRISPR-Cas12a, 2019
Knott, GJ; Cress, BF; Liu, J-J; Thornton, BW; Lew, RJ; Al-Shayeb, B et al.: Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a., 2019
Kundert, K; Lucas, JE; Watters, KE; Fellmann, C; Ng, AH; Heineike, BM et al.: Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs., 2019
Liu, Jun-Jie; Orlova, Natalia; Oakes, Benjamin L; Ma, Enbo; Spinner, Hannah B; Baney, Katherine LM et al.: CasX enzymes comprise a distinct family of RNA-guided genome editors, 2019
Liu, Tina Y; Liu, Jun-Jie; Aditham, Abhishek J; Nogales, Eva; Doudna, Jennifer A: Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble, 2019
Oakes, Benjamin L; Fellmann, Christof; Rishi, Harneet; Taylor, Kian L; Ren, Shawn M; Nadler, Dana C et al.: CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification, 2019
Ricci, CG; Chen, JS; Miao, Y; Jinek, M; Doudna, JA; McCammon, JA et al.: Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics., 2019
Ricci, Clarisse G; Chen, Janice S; Miao, Yinglong; Jinek, Martin; Doudna, Jennifer A; McCammon, J Andrew et al.: Molecular mechanism of off-target effects in CRISPR-Cas9, 2019
Thavalingam, Annoj; Cheng, Zhi; Garcia, Bianca; Huang, Xue; Shah, Megha; Sun, Wei et al.: Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2, 2019
Wright, AV; Wang, JY; Burstein, D; Harrington, LB; Paez-Espino, D; Kyrpides, NC et al.: A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System., 2019
Bondy-Denomy, Joseph; Davidson, Alan R; Doudna, Jennifer A; Fineran, Peter C; Maxwell, Karen L; Moineau, Sylvain et al.: A Unified Resource for Tracking Anti-CRISPR Names, 2018
Chen, Janice S; Ma, Enbo; Harrington, Lucas B; Da Costa, Maria; Tian, Xinran; Palefsky, Joel M et al.: CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity, 2018
Harrington, LB; Burstein, D; Chen, JS; Paez-Espino, D; Ma, E; Witte, IP et al.: Programmed DNA destruction by miniature CRISPR-Cas14 enzymes., 2018
Huang, Chun-Hao; Lee, Ko-Chuan; Doudna, Jennifer A: Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection, 2018
Kiessling, Laura L; Doudna, Jennifer A: Spotlight: A Conversation with Laura Kiessling and Jennifer Doudna, 2018
Knight, Spencer C; Tjian, Robert; Doudna, Jennifer A: Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies, 2018
Knott, Gavin J; Doudna, Jennifer A: CRISPR-Cas guides the future of genetic engineering, 2018
Lapinaite, Audrone; Doudna, Jennifer A; Cate, Jamie HD: Programmable RNA recognition using a CRISPR-associated Argonaute, 2018
Lintner, Nathanael G; McClure, Kim F; Petersen, Donna; Londregan, Allyn T; Piotrowski, David W; Wei, Liuqing et al.: Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain, 2018
Mancini, Andrew; Xavier-Magalhães, Ana; Woods, Wendy S; Nguyen, Kien-Thiet; Amen, Alexandra M; Hayes, Josie L et al.: Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner, 2018
Palermo, Giulia; Chen, Janice S; Ricci, Clarisse G; Rivalta, Ivan; Jinek, Martin; Batista, Victor S et al.: Key role of the REC lobe during CRISPR-Cas9 activation by 'sensing', 'regulating', and 'locking' the catalytic HNH domain., 2018
Palermo, Giulia; Chen, Janice S; Ricci, Clarisse G; Rivalta, Ivan; Jinek, Martin; Batista, Victor S et al.: Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain, 2018
Rouet, Romain; Thuma, Benjamin A; Roy, Marc D; Lintner, Nathanael G; Rubitski, David M; Finley, James E et al.: Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing, 2018
Strutt, Steven C; Torrez, Rachel M; Kaya, Emine; Negrete, Oscar A; Doudna, Jennifer A: RNA-dependent RNA targeting by CRISPR-Cas9, 2018
Tambe, Akshay; East-Seletsky, Alexandra; Knott, Gavin J; Doudna, Jennifer A; O’Connell, Mitchell R: RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a, 2018
Watters, Kyle E; Fellmann, Christof; Bai, Hua B; Ren, Shawn M; Doudna, Jennifer A: Systematic discovery of natural CRISPR-Cas12a inhibitors, 2018
Willsey, A Jeremy; Morris, Montana T; Wang, Sheng; Willsey, Helen R; Sun, Nawei; Teerikorpi, Nia et al.: The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders, 2018
Blair, John D; Hockemeyer, Dirk; Doudna, Jennifer A; Bateup, Helen S; Floor, Stephen N: Widespread Translational Remodeling during Human Neuronal Differentiation, 2017
Boyle, Evan A; Andreasson, Johan OL; Chircus, Lauren M; Sternberg, Samuel H; Wu, Michelle J; Guegler, Chantal K et al.: High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding, 2017
Burstein, David; Harrington, Lucas B; Strutt, Steven C; Probst, Alexander J; Anantharaman, Karthik; Thomas, Brian C et al.: New CRISPR–Cas systems from uncultivated microbes, 2017
Dagdas, Yavuz S; Chen, Janice S; Sternberg, Samuel H; Doudna, Jennifer A; Yildiz, Ahmet: A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9, 2017