Jennifer Doudna, UC Berkeley (Nobel Prize in Chemistry, 2020)
There are 104 publications in this collection, published between 2009 and 2022. Showing 51 - 100.
Doxzen, Kevin W; Doudna, Jennifer A: DNA recognition by an RNA-guided bacterial Argonaute, 2017
East-Seletsky, Alexandra; O’Connell, Mitchell R; Burstein, David; Knott, Gavin J; Doudna, Jennifer A: RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes, 2017
Harrington, Lucas B; Doxzen, Kevin W; Ma, Enbo; Liu, Jun-Jie; Knott, Gavin J; Edraki, Alireza et al.: A Broad-Spectrum Inhibitor of CRISPR-Cas9, 2017
Harrington, Lucas B; Paez-Espino, David; Staahl, Brett T; Chen, Janice S; Ma, Enbo; Kyrpides, Nikos C et al.: A thermostable Cas9 with increased lifetime in human plasma, 2017
Heler, Robert; Wright, Addison V; Vucelja, Marija; Bikard, David; Doudna, Jennifer A; Marraffini, Luciano A: Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response, 2017
Lee, Kunwoo; Conboy, Michael; Park, Hyo Min; Jiang, Fuguo; Kim, Hyun Jin; Dewitt, Mark A et al.: Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair, 2017
Lintner, Nathanael G; McClure, Kim F; Petersen, Donna; Londregan, Allyn T; Piotrowski, David W; Wei, Liuqing et al.: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain, 2017
Liu, Tina Y; Iavarone, Anthony T; Doudna, Jennifer A: RNA and DNA Targeting by a Reconstituted Thermus thermophiles Type III-A CRISPR-Cas System, 2017
Moreno-Mateos, Miguel A; Fernandez, Juan P; Rouet, Romain; Vejnar, Charles E; Lane, Maura A; Mis, Emily et al.: CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing, 2017
Shin, Jiyung; Jiang, Fuguo; Liu, Jun-Jie; Bray, Nicolas L; Rauch, Benjamin J; Baik, Seung Hyun et al.: Disabling Cas9 by an anti-CRISPR DNA mimic, 2017
Staahl, Brett T; Benekareddy, Madhurima; Coulon-Bainier, Claire; Banfal, Ashwin A; Floor, Stephen N; Sabo, Jennifer K et al.: Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes, 2017
Wright, Addison V; Liu, Jun-Jie; Knott, Gavin J; Doxzen, Kevin W; Nogales, Eva; Doudna, Jennifer A: Structures of the CRISPR genome integration complex, 2017
Carlson, Lars-Anders; Bai, Yun; Keane, Sarah C; Doudna, Jennifer A; Hurley, James H: Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies, 2016
Chen, Xingqi; Shen, Ying; Draper, Will; Buenrostro, Jason D; Litzenburger, Ulrike; Cho, Seung Woo et al.: ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing, 2016
Floor, Stephen N; Barkovich, Krister J; Condon, Kendall J; Shokat, Kevan M; Doudna, Jennifer A: Analog sensitive chemical inhibition of the DEAD-box protein DDX3., 2016
Floor, Stephen N; Doudna, Jennifer A: Tunable protein synthesis by transcript isoforms in human cells, 2016
Hochstrasser, Megan L; Taylor, David W; Kornfeld, Jack E; Nogales, Eva; Doudna, Jennifer A: DNA Targeting by a Minimal CRISPR RNA-Guided Cascade, 2016
Isaac, R Stefan; Jiang, Fuguo; Doudna, Jennifer A; Lim, Wendell A; Narlikar, Geeta J; Almeida, Ricardo: Nucleosome breathing and remodeling constrain CRISPR-Cas9 function, 2016
Jiang, Fuguo; Taylor, David W; Chen, Janice S; Kornfeld, Jack E; Zhou, Kaihong; Thompson, Aubri J et al.: Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage, 2016
Kaya, Emine; Doxzen, Kevin W; Knoll, Kilian R; Wilson, Ross C; Strutt, Steven C; Kranzusch, Philip J et al.: A bacterial Argonaute with noncanonical guide RNA specificity, 2016
Nelles, David A; Fang, Mark Y; O’Connell, Mitchell R; Xu, Jia L; Markmiller, Sebastian J; Doudna, Jennifer A et al.: Programmable RNA Tracking in Live Cells with CRISPR/Cas9, 2016
Oakes, Benjamin L; Nadler, Dana C; Flamholz, Avi; Fellmann, Christof; Staahl, Brett T; Doudna, Jennifer A et al.: Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch, 2016
Oh, Sekyung; Flynn, Ryan A; Floor, Stephen N; Purzner, James; Martin, Lance; T., Brian et al.: Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress, 2016
Singh, Digvijay; Sternberg, Samuel H; Fei, Jingyi; Doudna, Jennifer A; Ha, Taekjip: Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9, 2016
Baltimore, David; Berg, Paul; Botchan, Michael; Carroll, Dana; Charo, R Alta; Church, George et al.: Biotechnology. A prudent path forward for genomic engineering and germline gene modification., 2015
Doudna, Jennifer A; Gersbach, Charles A: Genome editing: the end of the beginning, 2015
Jiang, Fuguo; Doudna, Jennifer A: The structural biology of CRISPR-Cas systems, 2015
Ma, Enbo; Harrington, Lucas B; O’Connell, Mitchell R; Zhou, Kaihong; Doudna, Jennifer A: Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes, 2015
Schumann, Kathrin; Lin, Steven; Boyer, Eric; Simeonov, Dimitre R; Subramaniam, Meena; Gate, Rachel E et al.: Generation of knock-in primary human T cells using Cas9 ribonucleoproteins, 2015
Taylor, David W; Zhu, Yifan; Staals, Raymond HJ; Kornfeld, Jack E; Shinkai, Akeo; van der Oost, John et al.: Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning, 2015
Wilson, Ross C; Tambe, Akshay; Kidwell, Mary Anne; Noland, Cameron L; Schneider, Catherine P; Doudna, Jennifer A: Dicer-TRBP Complex Formation Ensures Accurate Mammalian MicroRNA Biogenesis, 2015
Wright, Addison V; Sternberg, Samuel H; Taylor, David W; Staahl, Brett T; Bardales, Jorge A; Kornfeld, Jack E et al.: Rational design of a split-Cas9 enzyme complex, 2015
Bai, Yun; Tambe, Akshay; Zhou, Kaihong; Doudna, Jennifer A: RNA-guided assembly of Rev-RRE nuclear export complexes, 2014
Hochstrasser, Megan L; Taylor, David W; Bhat, Prashant; Guegler, Chantal K; Sternberg, Samuel H; Nogales, Eva et al.: CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference, 2014
Jinek, Martin; Jiang, Fuguo; Taylor, David W; Sternberg, Samuel H; Kaya, Emine; Ma, Enbo et al.: Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation, 2014
Kapral, Gary J; Jain, Swati; Noeske, Jonas; Doudna, Jennifer A; Richardson, David C; Richardson, Jane S: New tools provide a second look at HDV ribozyme structure, dynamics and cleavage, 2014
Kidwell, Mary Anne; Chan, Jessica M; Doudna, Jennifer A: Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference Processing*, 2014
Kranzusch, Philip J; Lee, Amy SY; Wilson, Stephen C; Solovykh, Mikhail S; Vance, Russell E; Berger, James M et al.: Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity, 2014
Lin, Steven; Staahl, Brett T; Alla, Ravi K; Doudna, Jennifer A: Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery, 2014
Niewoehner, Ole; Jinek, Martin; Doudna, Jennifer A: Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases, 2014
Staals, Raymond HJ; Zhu, Yifan; Taylor, David W; Kornfeld, Jack E; Sharma, Kundan; Barendregt, Arjan et al.: RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus, 2014
Tambe, Akshay; Doudna, Jennifer; Pachter, Lior: Identifying RNA contacts from SHAPE-MaP by partial correlation analysis, 2014
Jinek, Martin; East, Alexandra; Cheng, Aaron; Lin, Steven; Ma, Enbo; Doudna, Jennifer: RNA-programmed genome editing in human cells, 2013
Lee, Ho Young; Zhou, Kaihong; Smith, Alison Marie; Noland, Cameron L; Doudna, Jennifer A: Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing, 2013
Lo, Te-Wen; Pickle, Catherine S; Lin, Steven; Ralston, Edward J; Gurling, Mark; Schartner, Caitlin M et al.: Precise and Heritable Genome Editing in Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions, 2013
Mortimer, Stefanie A; Doudna, Jennifer A: Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure, 2013
Pattanayak, Vikram; Lin, Steven; Guilinger, John P; Ma, Enbo; Doudna, Jennifer A; Liu, David R: High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity, 2013
Staals, Raymond HJ; Agari, Yoshihiro; Maki-Yonekura, Saori; Zhu, Yifan; Taylor, David W; van Duijn, Esther et al.: Structure and Activity of the RNA-Targeting Type III-B CRISPR-Cas Complex of Thermus thermophilus, 2013
Sun, Chaomin; Querol-Audí, Jordi; Mortimer, Stefanie A; Arias-Palomo, Ernesto; Doudna, Jennifer A; Nogales, Eva et al.: Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation, 2013
Taylor, David W; Ma, Enbo; Shigematsu, Hideki; Cianfrocco, Michael A; Noland, Cameron L; Nagayama, Kuniaki et al.: Substrate-specific structural rearrangements of human Dicer, 2013