Open Access Policy Deposits

Girard, Juliet R; Goins, Lauren M; Vuu, Dung M; Sharpley, Mark S; Spratford, Carrie M; Mantri, Shreya R et al.: Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis, 2021

Guo, Jingtao; Sosa, Enrique; Chitiashvili, Tsotne; Nie, Xichen; Rojas, Ernesto Javier; Oliver, Elizabeth et al.: Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment, 2021

Halaby, Steve; Martynowycz, Michael W; Zhu, Ziyue; Tretiak, Sergei; Zhugayevych, Andriy; Gonen, Tamir et al.: Microcrystal Electron Diffraction for Molecular Design of Functional Non-Fullerene Acceptor Structures, 2021

Hancock, GV; Liu, W; Peretz, L; Chen, D; Gell, JJ; Collier, AJ et al.: Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development, 2021

Hu, Rongfeng K; Zuo, Yanning; Ly, Truong; Wang, Jun; Meera, Pratap; Wu, Ye Emily et al.: An amygdala-to-hypothalamus circuit for social reward, 2021

Hughes, Michael P; Goldschmidt, Lukasz; Eisenberg, David S: Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils, 2021

Ichino, Lucia; Boone, Brandon A; Strauskulage, Luke; Harris, C Jake; Kaur, Gundeep; Gladstone, Matthew A et al.: MBD5 and MBD6 couple DNA methylation to gene silencing through the J-domain protein SILENZIO, 2021

Julio, Ashley R; Backus, Keriann M: New approaches to target RNA binding proteins, 2021

Kamagata, Kiyoto; Itoh, Yuji; Tan, Cheng; Mano, Eriko; Wu, Yining; Mandali, Sridhar et al.: Testing mechanisms of DNA sliding by architectural DNA-binding proteins: dynamics of single wild-type and mutant protein molecules in vitro and in vivo, 2021

Krall, Abigail S; Mullen, Peter J; Surjono, Felicia; Momcilovic, Milica; Schmid, Ernst W; Halbrook, Christopher J et al.: Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth, 2021

Kwon, Soo Bin; Ernst, Jason: Learning a genome-wide score of human–mouse conservation at the functional genomics level, 2021

Kwon, Soo Bin; Ernst, Jason: Single-nucleotide conservation state annotation of the SARS-CoV-2 genome, 2021

Lantz, Carter; Zenaidee, Muhammad A; Wei, Benqian; Hemminger, Zachary; Loo, Rachel R Ogorzalek; Loo, Joseph A: ClipsMS: An Algorithm for Analyzing Internal Fragments Resulting from Top-Down Mass Spectrometry, 2021

Lei, Hsiang-Ting; Mu, Xuelang; Hattne, Johan; Gonen, Tamir: A conformational change in the N terminus of SLC38A9 signals mTORC1 activation, 2021

Li, Fei; Egea, Pascal F; Vecchio, Alex J; Asial, Ignacio; Gupta, Meghna; Paulino, Joana et al.: Highlighting membrane protein structure and function: A celebration of the Protein Data Bank, 2021

Liu, Wanlu; Gallego-Bartolomé, Javier; Zhou, Yuxing; Zhong, Zhenhui; Wang, Ming; Wongpalee, Somsakul Pop et al.: Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase, 2021

Liu, Heng; Deepak, RNV Krishna; Shiriaeva, Anna; Gati, Cornelius; Batyuk, Alexander; Hu, Hao et al.: Molecular basis for lipid recognition by the prostaglandin D2 receptor CRTH2, 2021

Mandali, Sridhar; Johnson, Reid C: Control of the Serine Integrase Reaction: Roles of the Coiled-Coil and Helix E Regions in DNA Site Synapsis and Recombination, 2021

Markaki, Yolanda; Gan Chong, Johnny; Wang, Yuying; Jacobson, Elsie C; Luong, Christy; Tan, Shawn YX et al.: Xist nucleates local protein gradients to propagate silencing across the X chromosome, 2021

Martelly, William; Fellows, Bernice; Kang, Paul; Vashisht, Ajay; Wohlschlegel, James A; Sharma, Shalini: Synergistic roles for human U1 snRNA stem-loops in pre-mRNA splicing, 2021

Martynowycz, Michael W; Clabbers, Max TB; Unge, Johan; Hattne, Johan; Gonen, Tamir: Benchmarking the ideal sample thickness in cryo-EM, 2021

Martynowycz, Michael W; Shiriaeva, Anna; Ge, Xuanrui; Hattne, Johan; Nannenga, Brent L; Cherezov, Vadim et al.: MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP, 2021

Mayya, Vinay K; Flamand, Mathieu N; Lambert, Alice M; Jafarnejad, Seyed Mehdi; Wohlschlegel, James A; Sonenberg, Nahum et al.: microRNA-mediated translation repression through GYF-1 and IFE-4 in C. elegans development, 2021

McConnell, Scott A; McAllister, Rachel A; Amer, Brendan R; Mahoney, Brendan J; Sue, Christopher K; Chang, Chungyu et al.: Sortase-assembled pili in Corynebacterium diphtheriae are built using a latch mechanism, 2021

Mu, Xuelang; Gillman, Cody; Nguyen, Chi; Gonen, Tamir: An Overview of Microcrystal Electron Diffraction (MicroED), 2021

Mullen, Peter J; Garcia, Gustavo; Purkayastha, Arunima; Matulionis, Nedas; Schmid, Ernst W; Momcilovic, Milica et al.: SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition, 2021

Muroski, John M; Fu, Janine Y; Nguyen, Hong Hanh; Loo, Rachel R Ogorzalek; Loo, Joseph A: Leveraging Immonium Ions for Targeting Acyl‐Lysine Modifications in Proteomic Datasets, 2021

Murzinski, Emily; Saha, Ishika; Ding, Hui; Strugatsky, David; Hollibaugh, Ryan; Liu, Haixia et al.: In Search of Small Molecules That Selectively Inhibit MBOAT4., 2021

Nie, Minghua; Oravcová, Martina; Jami-Alahmadi, Yasaman; Wohlschlegel, James A; Lazzerini-Denchi, Eros; Boddy, Michael N: FAM111A induces nuclear dysfunction in disease and viral restriction, 2021

Palafox, Maria F; Desai, Heta S; Arboleda, Valerie A; Backus, Keriann M: From chemoproteomic‐detected amino acids to genomic coordinates: insights into precise multi‐omic data integration, 2021

Pezhouman, Arash; Nguyen, Ngoc B; Sercel, Alexander J; Nguyen, Thang L; Daraei, Ali; Sabri, Shan et al.: Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation, 2021

Quinodoz, Sofia A; Jachowicz, Joanna W; Bhat, Prashant; Ollikainen, Noah; Banerjee, Abhik K; Goronzy, Isabel N et al.: RNA promotes the formation of spatial compartments in the nucleus, 2021

Raam, Tara; Hong, Weizhe: Organization of neural circuits underlying social behavior: A consideration of the medial amygdala, 2021

Rayo, Josep; Gregor, Rachel; Jacob, Nicholas T; Dandela, Rambabu; Dubinsky, Luba; Yashkin, Alex et al.: Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones, 2021

Salas, Nehuén; Coceres, Veronica; Melo, Tuanne; Pereira-Neves, Antonio; Maguire, Vanina; Rodriguez, Tania et al.: VPS32, a member of the ESCRT complex, modulates adherence to host cells in the parasite Trichomonas vaginalis by affecting biogenesis and cargo sorting of released extracellular vesicles., 2021

Samarasinghe, Ranmal A; Miranda, Osvaldo A; Buth, Jessie E; Mitchell, Simon; Ferando, Isabella; Watanabe, Momoko et al.: Identification of neural oscillations and epileptiform changes in human brain organoids, 2021

Sawaya, Michael R; Hughes, Michael P; Rodriguez, Jose A; Riek, Roland; Eisenberg, David S: The expanding amyloid family: Structure, stability, function, and pathogenesis, 2021

Sharpley, Mark S; Chi, Fangtao; Hoeve, Johanna Ten; Banerjee, Utpal: Metabolic plasticity drives development during mammalian embryogenesis, 2021

Shen, Jia Z; Qiu, Zhixin; Wu, Qiulian; Finlay, Darren; Garcia, Guillermina; Sun, Dahui et al.: FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells, 2021

Shipps, Catharine; Kelly, H Ray; Dahl, Peter J; Yi, Sophia M; Vu, Dennis; Boyer, David et al.: Intrinsic electronic conductivity of individual atomically resolved amyloid crystals reveals micrometer-long hole hopping via tyrosines, 2021

Smith, Lloyd M; Agar, Jeffrey N; Chamot-Rooke, Julia; Danis, Paul O; Ge, Ying; Loo, Joseph A et al.: The Human Proteoform Project: Defining the human proteome, 2021

Sun, Victoria; Sharpley, Mark; Kaczor-Urbanowicz, Karolina E; Chang, Patrick; Montel-Hagen, Amélie; Lopez, Shawn et al.: The Metabolic Landscape of Thymic T Cell Development In Vivo and In Vitro, 2021

Sun, Fei; Sun, Terrence; Kronenberg, Michael; Tan, Xianglong; Huang, Chengyang; Carey, Michael F: The Pol II preinitiation complex (PIC) influences Mediator binding but not promoter–enhancer looping, 2021

Tetreau, Guillaume; Sawaya, Michael R; De Zitter, Elke; Andreeva, Elena A; Banneville, Anne-Sophie; Schibrowsky, Natalie et al.: De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals, 2021

Vadivel, Kanagasabai; Schmidt, Amy; Cascio, Duilio; Padmanabhan, Kaillathe; Krishnaswamy, Sriram; Brandstetter, Hans et al.: Structure of human factor VIIa-soluble tissue factor with calcium, magnesium and rubidium., 2021

Vélez-Ramírez, Daniel E; Shimogawa, Michelle M; Ray, Sunayan S; Lopez, Andrew; Rayatpisheh, Shima; Langousis, Gerasimos et al.: APEX2 Proximity Proteomics Resolves Flagellum Subdomains and Identifies Flagellum Tip-Specific Proteins in Trypanosoma brucei, 2021

Wang, Huan; Chan, Tracey W; Vashisht, Ajay A; Drew, Brian G; Calkin, Anna C; Harris, Thurl E et al.: Lipin 1 modulates mRNA splicing during fasting adaptation in liver, 2021

Wendimu, Menbere Y; Alqinyah, Mohammed; Vella, Stephen; Dean, Phillip; Almutairi, Faris; Davila-Rivera, Roseanne et al.: RGS10 physically and functionally interacts with STIM2 and requires store-operated calcium entry to regulate pro-inflammatory gene expression in microglia, 2021

Wu, Ye Emily; Dang, James; Kingsbury, Lyle; Zhang, Mingmin; Sun, Fangmiao; Hu, Rongfeng K et al.: Neural control of affiliative touch in prosocial interaction, 2021

Xiao, Xu; Kim, Youngjae; Romartinez-Alonso, Beatriz; Sirvydis, Kristupas; Ory, Daniel S; Schwabe, John WR et al.: Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms, 2021